The U.S. Food and Drug Administration has expanded indications for AbbVie's Rinvoq (upadacitinib) to now include pediatric patients (ages 2 years and older) with polyarticular juvenile idiopathic arthritis (pJIA) and psoriatic ...
Jun 24, 2024
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Recent advances in genomic sequencing have revealed that 5–15% of children with cancer have an underlying genetic predisposition. Although genetic predispositions increase the risk for new tumors, it has been unclear when ...
Jun 21, 2024
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The U.S. Food and Drug Administration has approved Augtyro (repotrectinib), a next-generation tyrosine kinase inhibitor (TKI), for the treatment of patients with neurotrophic tyrosine receptor kinase (NTRK)-positive locally ...
Jun 21, 2024
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Due to differences in clinical presentation and limited knowledge, diagnosing Sjögren's disease in children can be challenging. Although dysregulation of multiple immune response pathways has been shown in adults, few studies ...
Jun 14, 2024
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Patients with asthma commonly suffer from allergic diseases, with an estimated 80% suffering from allergic rhinitis. Asthma and allergic rhinitis share common characteristics, and allergic rhinitis is a risk factor for asthma ...
Jun 13, 2024
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For Spanish and Portuguese, machine translation platforms have comparable performance to professional translations for discharge instructions for pediatric conditions, but considerable shortcomings were seen for Haitian Creole, ...
Jun 13, 2024
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The MEK inhibitor trametinib (Mekinist) was an effective treatment for pediatric patients with relapsed or refractory juvenile myelomonocytic leukemia (JMML) enrolled in a Phase II clinical trial, with seven of 10 patients ...
Jun 13, 2024
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While most cell types experience a functional decline after years of proliferation and replication, T cells can proliferate seemingly indefinitely and without detriment.
Jun 12, 2024
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The U.S. Food and Drug Administration has approved Tris Pharma's once-daily Onyda XR (clonidine hydrochloride) as the first liquid, nonstimulant treatment for attention-deficit/hyperactivity disorder (ADHD).
Jun 4, 2024
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Little is known about the genetics and biology of chordoma, a rare and aggressive bone tumor. Chordomas occur in approximately one in a million people in the U.S. a year and 5% of these are in children. These tumors can arise ...
May 31, 2024
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