Many types of human cancers exhibit changes in kinase and phosphatase balances. Drugs that inhibit kinase activity have shown success in the clinic as cancer therapeutics, but the phosphatases still remain a largely underexploited ...
Aug 12, 2020
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157
Researchers at the University of Arizona have discovered that metformin, a drug commonly used to treat type 2 diabetes, might also be used to treat heart failure with preserved ejection fraction (HFpEF), a condition that ...
Dec 19, 2018
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Tiny deviations in the body's cells can sometimes have severe consequences. Researchers from Berlin have discovered why cells from patients suffering from the rare muscular disease myotubular myopathy cannot function properly. ...
Jan 21, 2016
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Huntington's disease is a progressive and aggressively debilitating brain disorder that causes uncontrolled movements, psychological problems, and loss of cognition. It is caused by a mutation in the gene that encodes the ...
Aug 5, 2020
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Researchers led by Julian E. Stelzer, PhD, associate professor in the department of physiology and biophysics at Case Western Reserve University School of Medicine, have found a new target for drug developers seeking straightforward ...
Apr 4, 2017
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A large international collaboration led by researchers from the Johns Hopkins Kimmel Cancer Center has identified promising new targets for pancreatic cancer treatment and early diagnosis after examining various aspects of ...
Sep 20, 2021
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An investigational drug that blocks intestinal phosphate absorption may help reduce the dangerously high blood levels of phosphate commonly seen in patients with kidney failure. The findings appear in an upcoming issue of ...
Mar 7, 2019
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Our bodies have the ability to modify the contacts between neurons. Among other things, this is how it prevents brain activity from getting out of control. Researchers from the University Hospital Bonn, together with a team ...
Apr 20, 2022
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To put the COVID-19 pandemic in the rearview mirror and prevent other coronaviruses from causing havoc, the world needs an arsenal of measures to prevent and treat these infections. To develop new medications, researchers ...
Jul 13, 2022
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As components of two entirely separate systems in the body, you wouldn't think ovaries have much in common with bones. But it turns out they do – and their commonalities may help explain why dwarfs such as actors Peter ...
Feb 5, 2018
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