A research team at Massachusetts Eye and Ear has shown that microglia, the primary immune cells of the brain and retina, play a protective role in response to retinal detachment. Retinal detachment and subsequent degeneration ...
Jun 18, 2018
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A new study that compared six of the most promising adeno-associated viral (AAV) gene therapy vectors in human retinal organoid models showed clear distinctions in the efficiency of gene transfer to both retinal pigment epithelial ...
Jun 13, 2018
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The brain's ability to form new neural connections, called neuroplasticity, is crucial to recovery from some types of brain injury, but this process is hard to study and remains poorly understood. A new study of neural circuit ...
May 24, 2018
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Researchers from the University of Pennsylvania have developed a gene therapy that successfully treats a form of macular degeneration in a canine model. The work sets the stage for translating the findings into a human therapy ...
Mar 5, 2018
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Scientists at the National Eye Institute (NEI), part of the National Institutes of Health, report that tiny tube-like protrusions called primary cilia on cells of the retinal pigment epithelium (RPE)—a layer of cells in ...
Jan 2, 2018
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Gene therapy holds promise for treating a variety of diseases, including some inherited blinding conditions. But for a gene therapy to be effective, one must know the precise gene responsible for a given individual's disorder ...
Dec 20, 2017
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For decades, scientists have known that blue light will make fruit flies go blind, but it wasn't clear why. Now, a Purdue University study has found how this light kills cells in the flies' eyes, and that could prove a useful ...
Dec 18, 2017
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An international research team headed by Thomas Münch from Tübingen University found the contribution of rod photoreceptors in mouse retinas to be much greater than previously assumed. Rods cannot distinguish between colours ...
Nov 27, 2017
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Researchers added a scaffold/matrix attachment region (S/MAR) to a conventional adeno-associated virus (AAV) vector used for gene transfer, and the modified vectors were able to establish colonies and maintain long-term transgene ...
Sep 22, 2017
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Dr. Wolf M. Harmening from University Eye Hospital Bonn, together with American colleagues, studied color vision by probing individual sensory cells - photoreceptors - in the human eye. The results confirm that the photoreceptor ...
Sep 6, 2017
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