Diseases, Conditions, Syndromes

Orexin receptor 2 agonist improves sleepiness in narcolepsy

For patients with narcolepsy type 1, an orexin receptor 2 agonist, TAK-994, improves measures of sleepiness and cataplexy over eight weeks compared with placebo but is associated with hepatotoxic adverse events, according ...

Medications

Mifepristone efficacious for adenomyosis

For patients with adenomyosis, mifepristone is efficacious and has acceptable tolerability, according to a study published online June 12 in JAMA Network Open.

Medications

Peresolimab found to be efficacious for rheumatoid arthritis

Peresolimab, a humanized immunoglobulin G1 monoclonal antibody designed to stimulate the endogenous programmed cell death protein 1 (PD-1) inhibitory pathway, is efficacious for patients with rheumatoid arthritis, according ...

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