Alzheimer's disease & dementia

Brain changes may help track dementia, even before diagnosis

Even before a dementia diagnosis, people with mild cognitive impairment may have different changes in the brain depending on what type of dementia they have, according to a study published in the September 11, 2019, online ...

Cardiology

Microbes may play a role in heart attack onset

Microorganisms in the body may contribute to destabilisation of coronary plaques and subsequent heart attack, according to late breaking research presented today at ESC Congress 2019 together with the World Congress of Cardiology.

Medical research

Study offers promising approach to reducing plaque in arteries

In a new Yale-led study, investigators have revealed previously unknown factors that contribute to the hardening of arteries and plaque growth, which cause heart disease. Their insight is the basis for a promising therapeutic ...

Alzheimer's disease & dementia

New drug targets early instigator of Alzheimer's disease

Over a hundred years after they were first identified, two ominous signposts of Alzheimer's disease (AD) remain central topics of research—both formed by sticky accumulations of protein in the brain. Amyloid beta solidifies ...

Neuroscience

Tissue model reveals role of blood-brain barrier in Alzheimer's

Beta-amyloid plaques, the protein aggregates that form in the brains of Alzheimer's patients, disrupt many brain functions and can kill neurons. They can also damage the blood-brain barrier—the normally tight border that ...

Alzheimer's disease & dementia

Direct toxic action of beta-amyloid identified

Hyperactive neurons in specific areas of the brain are believed to be an early perturbation in Alzheimer's disease. For the first time, a team from the Technical University of Munich (TUM) was able to explain the reasons ...

Alzheimer's disease & dementia

Blood tests for Alzheimer's: Why new studies are encouraging

Many people who have problems with their memory, especially if they are elderly, worry that they have Alzheimer's disease, which afflicts at least 5.5 million people in the U.S. and brings tremendous burdens to families as ...

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