Alzheimer's disease & dementia

Researchers successfully reverse Alzheimer's disease in mouse model

A team of researchers from the Cleveland Clinic Lerner Research Institute have found that gradually depleting an enzyme called BACE1 completely reverses the formation of amyloid plaques in the brains of mice with Alzheimer's ...

Alzheimer's disease & dementia

Alzheimer's disease is a 'double-prion disorder,' study shows

Two proteins central to the pathology of Alzheimer's disease act as prions—misshapen proteins that spread through tissue like an infection by forcing normal proteins to adopt the same misfolded shape—according to new ...

Alzheimer's disease & dementia

New Alzheimer's-related memory disorder identified

A multi-institutional study has defined and established criteria for a new neurological disease closely resembling Alzheimer's disease called primary age-related tauopathy (PART). Patients with PART develop cognitive impairment ...

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