Alzheimer's disease & dementia

Amyloid beta in the brain of individuals with Alzheimer's disease

While there may not be a consensus whether deposition of amyloid beta contributes to Alzheimer's disease or is a consequence of it, there is agreement that something else is promoting the process. Other proteins are often ...

Oncology & Cancer

DGK-alpha helps cancer cells gain traction and mobilize

Metastasizing cancer cells often express integrins that provide better traction. A new study in The Journal of Cell Biology reveals how a lipid-converting enzyme helps the cells mobilize these integrins.

Medical research

Notre Dame researchers report fundamental malaria discovery

A team of researchers led by Kasturi Haldar and Souvik Bhattacharjee of the University of Notre Dame's Center for Rare and Neglected Diseases has made a fundamental discovery in understanding how malaria parasites cause deadly ...

Oncology & Cancer

Towards more effective treatment for multiple myeloma

A new study from SUNY Downstate Medical Center in Brooklyn, New York, shows that MAL3-101, a recently developed inhibitor of the heat shock protein 70 (Hsp70), appears to have potent anti-tumor effects on multiple myeloma, ...

Health

Addressing how cigarettes cause cardiovascular disease

Although cigarette smoking has long been linked to cardiovascular disease, scientists are still on the lookout for insights into how smoking causes this disease. A team of researchers at Pacific Northwest National Laboratory ...

Medical research

Awaiting orders to retaliate

(Medical Xpress) -- When immune system B cells are alerted to the presence of a threat within the body, they form structures called germinal centers, which serve as ad hoc headquarters for marshaling a targeted immune response. ...

Oncology & Cancer

Addressing high false-positive rates for mammograms

We've heard it repeatedly: early detection is key to surviving breast cancer. But even with recent advances in mammography, finding indications of breast cancer before it can metastasize remains a problem. Scientists at Pacific ...

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