Several new malaria drugs under development share a common feature: they promote an influx of sodium ions into Plasmodium parasites that have invaded red blood cells and multiply there. A study published on May 26th in PLOS ...
May 26, 2016
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Plasmodium falciparum, the parasite that causes the deadliest form of malaria in humans, is a master evader, and has dodged all attempts at an effective and durable vaccine. Now, using a sophisticated method that characterizes ...
Mar 17, 2023
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The essential malaria drug artemisinin acts like a "ticking time bomb" in parasite cells—but in the half a century since the drug was introduced, malaria-causing parasites have slowly grown less and less susceptible to ...
Sep 23, 2020
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Scientists uncover a port of liver entry for malaria parasites in a report published in The Journal of Experimental Medicine. If these results hold up in humans, drugs that target this entry protein might help prevent the ...
Jul 27, 2015
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Scientists at the Wellcome Trust Sanger Institute and their collaborators have discovered genetic markers in malaria parasites linked with resistance to the anti-malarial drug piperaquine. Reported in Lancet Infectious Diseases, ...
Nov 3, 2016
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Malaria parasites survive the mosquito-free dry season by waiting silently in humans for the return of the rainy season that brings back with it mosquitoes. New research, by an international team including Penn State scientists, ...
Oct 27, 2020
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The plasmodium parasite, which transmits malaria to humans through infected mosquitos, triggers changes in human genes that alter the body's adaptive immune response to malarial infections, according to a team of researchers ...
Oct 9, 2020
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Parasites in the genus Plasmodium, which cause malaria, are transmitted to humans through bites from infected mosquitoes. The parasites acclimatize to these two completely different hosts because the plasticity of their genome ...
Jan 3, 2020
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Two experimental malaria vaccines are not only safe for humans, one of those immunizations prompted a slowing of the malaria parasite's replication in the bloodstream of clinical trial participants, scientists have found ...
Using live but weakened malaria parasites as the basis of a vaccine represents a potentially encouraging anti-malaria strategy, according to results of follow-up animal studies performed after the conclusion of a recent clinical ...
Sep 8, 2011
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