A large international team of researchers has found a small molecule compound that has proven to be effective in treating malaria in mice. In their paper published in the journal Science Translational Medicine, the group ...
A new study led by Maria Manuel Mota, group leader at Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal), now shows that malaria parasites secrete the protein EXP2 to make their entry into hepatocytes. These ...
Nov 6, 2020
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Malaria parasites survive the mosquito-free dry season by waiting silently in humans for the return of the rainy season that brings back with it mosquitoes. New research, by an international team including Penn State scientists, ...
Oct 27, 2020
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The plasmodium parasite, which transmits malaria to humans through infected mosquitos, triggers changes in human genes that alter the body's adaptive immune response to malarial infections, according to a team of researchers ...
Oct 9, 2020
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The essential malaria drug artemisinin acts like a "ticking time bomb" in parasite cells—but in the half a century since the drug was introduced, malaria-causing parasites have slowly grown less and less susceptible to ...
Sep 23, 2020
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Through investigating the causes of brain swelling in cerebral malaria—a devastating parasitic disease that is fatal for one in five children—scientists have found a potential new treatment approach that could be safely ...
Jun 25, 2020
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In an unprecedented first, scientists at Seattle Children's Research Institute have developed a genetically attenuated parasite (GAP) that arrests late in the liver stage of human malaria. Their findings published in JCI ...
Jun 16, 2020
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A potential new approach for preventing malaria is on the horizon with the discovery that drugs currently used to kill cancer cells can also kill malaria-infected liver cells.
Apr 1, 2020
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Parasites in the genus Plasmodium, which cause malaria, are transmitted to humans through bites from infected mosquitoes. The parasites acclimatize to these two completely different hosts because the plasticity of their genome ...
Jan 3, 2020
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Immunological signatures can predict whether malaria-infected children will develop fever or other symptoms, suggests a study publishing September 3 in the journal Immunity. Surprisingly, activation of the well-known tumor-suppressor ...
Sep 3, 2019
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