Neuroscience

Research reveals drug targets for memory enhancement

Bristol-led research has identified specific drug targets within the neural circuits that encode memories, paving the way for significant advances in the treatment of a broad spectrum of brain disorders.

Neuroscience

Imaging single spine structural plasticity at the nanoscale level

For most, the relentless snapping of camera shutters is an all-too-familiar sound associated with trips and vacations. When venturing to a new place, travelers everywhere are constantly on the search for that picture-perfect, ...

Arthritis & Rheumatism

Nasal cartilage used to relieve osteoarthritis in the knee

Cartilage cells from the nasal septum can not only help repair cartilage injuries in the knee—according to researchers from the University of Basel and the University Hospital of Basel, they can also withstand the chronic ...

Psychology & Psychiatry

Discovery points to ketamine's long-term antidepressant effects

Building on recent research confirming how ketamine induces rapid antidepressant action, Professor of Pharmacology Lisa Monteggia and her collaborators show how the molecular mechanism of the gene MeCP2 and associated synaptic ...

Medical research

The key role of astrocytes in cognitive development

Astrocytes have long been considered as mere support cells for neurons. In recent years, the study of astrocytes has grown, gradually revealing their importance in brain function. Researchers from Inserm, CNRS and Collège ...

Medical research

Shootin1a—the missing link underlying learning and memory

In neurons, changes in the size of dendritic spines—small cellular protrusions involved in synaptic transmission—are thought to be a key mechanism underlying learning and memory. However, the specific way in which these ...

Neuroscience

Synaptic transmission: Not a one-way street

Information flows in a well-defined direction in the brain: Chemical and electrical signals are passed from one neuron to the other across the synapse, from the pre-synaptic to the post-synaptic neuron. Now, Peter Jonas and ...

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