More than 3 million Americans have glaucoma, a serious eye condition causing vision loss. Using human stem cell models, researchers at Indiana University School of Medicine found they could analyze deficits within cells damaged ...
Jun 11, 2020
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R-loops are unique structures in the cell, composed of RNA–DNA hybrids and a displaced single-stranded DNA, that are commonly found around transcribed genes. However, R-loops are also dynamic and widespread entities that ...
Jun 11, 2020
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By developing a lab-engineered model of the human blood-brain barrier (BBB), neuroscientists at MIT's Picower Institute for Learning and Memory have discovered how the most common Alzheimer's disease risk gene causes amyloid ...
Jun 8, 2020
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For more than 40 years, scientists and commercial companies have been recreating human skin in laboratories around the world. Yet all of these products lack important aspects of normal skin—hair, nerves, and fat.
Jun 4, 2020
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Researchers at Mount Sinai have discovered that human acute myeloid leukemia (AML) stem cells are dependent on a transcription factor known as RUNX1, potentially providing a new therapeutic target to achieve lasting remissions ...
Jun 2, 2020
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Patients with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, lose muscle control as nerve cells or neurons in the brain and spinal cord degenerate and can no longer send signals to muscles. Previous ...
May 28, 2020
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A new study shows that when specific human brain cells are transplanted into animal models of multiple sclerosis and other white matter diseases, the cells repair damage and restore function. The study provides one of the ...
May 19, 2020
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Research from the University of Sheffield has given new insight into the cause of mutations in pluripotent stem cells and potential ways of stopping these mutations from occurring.
May 14, 2020
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Reprogramming a patient's own skin cells to replace cells in the brain that are progressively lost during Parkinson's disease (PD) has been shown to be technically feasible, reports a team of investigators from McLean Hospital ...
May 13, 2020
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An interdisciplinary team of researchers at the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at UCLA has developed a first-of-its-kind roadmap of how human skeletal muscle develops, including ...
May 11, 2020
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