Researchers have been using organoids—3D organ-like, tightly-packed cell cultures—as models to study organ development, disease and drug discovery with excellent success. However, most existing imaging methods are limited ...
Mar 14, 2022
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Researchers at Indiana University School of Medicine, in collaboration with the University of Alabama at Birmingham and five other institutions, are investigating novel regenerative medicine approaches to better manage vascular ...
Mar 10, 2022
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Maturity-onset diabetes of the young (MODY) is a disease caused by single-gene mutations. The genes typically affected by MODY are important for the development and function of beta-cells, which are crucial for maintaining ...
Mar 2, 2022
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Embryonic stem cells and other pluripotent cells divide rapidly and have the capacity to become nearly any cell type in the body. Scientists have long sought to understand the signals that prompt stem cells to switch off ...
Feb 21, 2022
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During the past ten years, scientists who study how the human body develops and functions on the most basic level have enjoyed a renaissance of sorts, thanks to structures called organoids—tiny 3D models of organs developed ...
Feb 16, 2022
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Biomedical engineers at Duke University have developed a method to study how key cells in the kidneys become injured and deformed. The new model has revealed a significant mechanism behind severe kidney disease and pointed ...
Jan 26, 2022
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Utilizing cutting-edge proteomics, researchers at the Buck Institute and elsewhere have mapped the "tau interactome" uncovering new findings about the role of tau in neurodegenerative disease. Publishing in Cell, scientists ...
Jan 20, 2022
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Researchers at the National Eye Institute (NEI) have developed the first patient-derived stem cell model for studying eye conditions related to oculocutaneous albinism (OCA). The model's development is described in the January ...
Jan 11, 2022
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Scientists have discovered that gene therapy and the diabetes drug metformin may be potential treatments for late-onset retinal degeneration (L-ORD), a rare, blinding eye disease. Researchers from the National Eye Institute ...
Dec 9, 2021
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Interim results from a multicenter clinical trial demonstrate insulin secretion from engrafted cells in patients with type 1 diabetes. The safety, tolerability, and efficacy of the implants, which consisted of pancreatic ...
Dec 2, 2021
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