A major hurdle in gene therapy is the efficient integration of a corrected gene into a patient's genome without mutating off-target sites. In a paper published today in Genome Research, scientists have used CRISPR/Cas genome ...
Aug 5, 2014
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Researchers from UC Davis School of Medicine and Shriners Hospitals for Children – Northern California have identified a group of cells in the brain that they say plays an important role in the abnormal neuron development ...
Jul 18, 2014
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The ability to reliably and safely make in the laboratory all of the different types of cells in human blood is one key step closer to reality.
Jul 14, 2014
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Johns Hopkins researchers have begun to connect the dots between a schizophrenia-linked genetic variation and its effect on the developing brain. As they report July 3 in the journal Cell Stem Cell, their experiments show ...
Jul 3, 2014
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Scientists from the groups of Botond Roska and Witold Filipowicz at the Friedrich Miescher Institute for Biomedical Research have resolved the mechanism controlling the maintenance of the light sensitive "antennas" of photoreceptors ...
Jul 2, 2014
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Scientists at the University at Buffalo have identified the single transcription factor or "master switch" that initiates the critical myelination process in the brain. The research will be published online in Proceedings ...
Jun 30, 2014
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By switching off a single gene, scientists at Columbia University's Naomi Berrie Diabetes Center have converted human gastrointestinal cells into insulin-producing cells, demonstrating in principle that a drug could retrain ...
Jun 30, 2014
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Japanese stemcell scientists have succeeded in slowing the deterioration of mice with motor neurone disease, possibly paving the way for eventual human treatment, according to a new paper.
Jun 27, 2014
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One of the biggest challenges for medical researchers studying the effectiveness of stem cell therapies is that transplants or grafts of cells are often rejected by the hosts. This rejection can render experiments useless, ...
Jun 4, 2014
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Children with progeria, a rare disorder that causes premature aging, die in their teens of ailments that are common in octogenarians: heart failure and stroke. Kan Cao, a University of Maryland assistant professor of cell ...
May 19, 2014
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