Genetics

First multi-whole-genome study of IBD in African Americans

In African Americans, the genetic risk landscape for inflammatory bowel disease (IBD) is very different from that of people with European ancestry, according to results of the first whole-genome study of IBD in African Americans. ...

Cardiology

BMI over time beats genetics in predicting future obesity

The promise of genetic testing is charming doctors and patients who are eager to finally make a dent in rising obesity rates. After all, weighing too much is a risk factor for lots of chronic diseases and greatly affects ...

Gastroenterology

Polygenic risk score more strongly linked to early-onset CRC

(HealthDay)—A polygenic risk score (PRS), developed from 95 colorectal cancer (CRC)-associated genetic risk variants, is more strongly associated with early- than late-onset cancer, especially in the absence of family history, ...

Psychology & Psychiatry

Polygenic risk score improves psychosis risk prediction

A new study led by researchers at the University of North Carolina at Chapel Hill has found that that using a polygenic risk score (PRS) based on data from genome-wide association studies (GWAS) improves psychosis risk prediction ...

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