The potassium channel KCNQ3 is required for our brain to generate accurate spatial maps. In mice, defects in KCNQ3 function have measurable effects on the internal navigation system. The findings of a research team including ...
Aug 12, 2021
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In polymicrogyria, the cortex of the brain has many irregular, small folds (gyria) and disorganization of its layers. Many affected children have severe developmental delay, intellectual disabilities, and epilepsy, and many ...
Jun 14, 2021
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Dozens of commonly used drugs, including antibiotics, antinausea and anticancer medications, have a potential side effect of lengthening the electrical event that triggers contraction, creating an irregular heartbeat, or ...
May 14, 2021
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Neuroscientists at the University of Pittsburgh Brain Institute have identified a novel drug that could protect the brain during and after a stroke.
Jul 1, 2020
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Ion channels, which allow potassium and sodium ions to flow in and out of cells, are crucial in neuronal 'firing' in the central nervous system and for brain and heart function. These channels use a "ball-and-chain" mechanism ...
Mar 18, 2020
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137
University of Alabama at Birmingham researchers, for the first time ever, have achieved patch-clamp studies of an elusive part of mammalian myelinated nerves called the Nodes of Ranvier. At the nodes, they found unexpected ...
Nov 6, 2019
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Researchers have described a new mechanism which induces the self-killing of cancer cells by perturbing ion homeostasis. A research team from the KAIST Department of Biochemical Engineering has developed helical polypeptide ...
Aug 28, 2019
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Retinal ganglion cells (RGCs) make up the optic nerve. When RGCs degenerate due to elevated intraocular pressure caused by glaucoma, vision is lost.
Jul 17, 2019
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A new study provides potential new targets for treating epilepsy and new fundamental insights into the relationship between neurons and their glial "helper" cells. In eLife, scientists at MIT's Picower Institute for Learning ...
Apr 30, 2019
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Researchers at UCL have shown for the first time that mammals detect different intensities of cold using distinct sensory neuron systems, a finding which could lead to the development of new drugs to treat cold pain.
Apr 24, 2019
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