A preclinical study led by scientists at Sanford Burnham Prebys has established that AAV8-TNAP-D10—a gene therapy that replaces a key enzyme found in bone—may be a safe and effective single-dose treatment for hypophosphatasia ...
Jun 7, 2021
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Breast cancer is the leading cause of cancer death in women around the world, responsible for 1,700 deaths every day. Although the vast majority of breast cancers are treatable, the most aggressive subtype—triple negative ...
Jun 7, 2021
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In pharmaceutical research, small tissue spheres are used as mini-organ models for reproducible tests. TU Wien has found a way to develop a reliable standard for these tissue samples.
May 26, 2021
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An experimental flu vaccine consisting of billions of tiny spherical sacs that carry infection-fighting proteins throughout the body has proven effective in preclinical studies.
May 24, 2021
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Type 2 diabetes patients who also have asthma are benefitting from a diabetes medication, typically given to help the pancreas produce more insulin, that also improves asthma symptoms and may reduce lung and airway inflammation.
May 21, 2021
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The Lundquist Institute spinoff start-up company Vitalex Biosciences, founded by researcher Dr. Ashraf Ibrahim, is producing an antibody that stems the spread of mucormycosis, a deadly fungal infection with an overall mortality ...
May 17, 2021
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A class of drugs that inhibits breast cancer progression when used with hormonal therapy might also boost the effectiveness of immune therapy in cases of recurrent, metastatic breast cancer, according to a new study led by ...
May 10, 2021
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The anti-diabetic drug phenformin may prompt stronger cancer-fighting activities than its sister compound metformin, a finding that could have major implications for current and future clinical trials investigating both agents ...
Apr 14, 2021
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New data published by researchers at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James) suggests that an oral drug currently used ...
Apr 13, 2021
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A preclinical study led by researchers at The University of Texas MD Anderson Cancer Center shows an antibody-drug conjugate (ADC) targeting surface protein MT1-MMP can act as a guided missile in eradicating osteosarcoma ...
Apr 12, 2021
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