Structural insights into a potent antimalarial drug candidate's interaction with the malaria parasite Plasmodium falciparum have paved the way for drug-resistant malaria therapies, according to a new study by researchers ...
Jan 18, 2024
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A new research paper was published on the cover of Aging titled, "Effects of resveratrol on in vitro circadian clock gene expression in young and older human adipose-derived progenitor cells."
Jan 16, 2024
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The Organoid group at the Hubrecht Institute produced the first organoid model of the human conjunctiva. These organoids mimic the function of the actual human conjunctiva, a tissue involved in tear production. Using their ...
Jan 11, 2024
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Hard-to-detect colorectal pre-cancerous lesions known as serrated polyps, and the aggressive tumors that develop from them, depend heavily on the ramped-up production of cholesterol, according to a preclinical study from ...
Dec 13, 2023
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The Malaghan Institute of Medical Research, in collaboration with Wellington Zhaotai Therapies Limited, today announced results of its phase 1 dose escalation trial of a new third generation anti-CD19 chimeric antigen receptor ...
Dec 11, 2023
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Early results from a Phase I clinical trial of AT101, a new CAR T cell therapy that uses a distinct binding mechanism to target CD19, show a 100% complete response (CR) rate at the higher dose levels studied in the trial, ...
Dec 11, 2023
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A preclinical study by Weill Cornell Medicine investigators shows that a specific human genetic variant of a receptor that stimulates insulin release may help individuals resist obesity. The researchers discovered that this ...
Dec 7, 2023
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Semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1RA) originally formulated to treat diabetes, has gained traction as the latest and greatest weight loss drug. Among the hype, anecdotal observations from patients ...
Dec 5, 2023
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Lidocaine—often used as a numbing agent for outpatient medical procedures—activates certain bitter taste receptors through two unique mechanisms that result in cancer cell death, according to researchers from the Perelman ...
Nov 22, 2023
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Preclinical research published in the Journal for ImmunoTherapy of Cancer points to a promising new treatment option for people with pancreatic cancer. Researchers from VCU Massey Comprehensive Cancer Center and the VCU Institute ...
Nov 10, 2023
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