Within cells infected by Kaposi sarcoma herpesvirus (KSHV), the human protein CADM1 interacts with viral proteins to promote chronic inflammation, which plays a major role in the development of cancers caused by KSHV. Richard ...
Apr 26, 2018
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Biomedical engineers at Duke University have demonstrated that metastatic cancer cells can reprogram their metabolism to thrive in new organs. Specifically, the research shows that cells originating from colorectal cancer ...
Apr 26, 2018
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Testing the safety of medicines and chemicals on organ-like structures developed from various types of stem cells could reduce the reliance on animal testing and streamline chemical and drug development, according to scientists ...
Apr 11, 2018
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Scientists at the UNC School of Medicine and NC State have created an injectable gel-like scaffold that can hold combination chemo-immunotherapeutic drugs and deliver them locally to tumors in a sequential manner. The results ...
Feb 21, 2018
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New research from The Scripps Research Institute (TSRI) may give scientists a chance to target tumors before they metastasize. The study, published recently in the Nature research journal Oncogene, shows that a protein called ...
Feb 8, 2018
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Glioblastoma multiforme is the most common and aggressive primary brain tumor and has one of the worst survival rates of all cancers. Despite surgery, radiation and chemotherapy, these tumors virtually always become resistant ...
Feb 5, 2018
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Actively growing tumors have a high demand for oxygen and nutrients. Therefore, they stimulate the growth of blood vessels through a process called angiogenesis. If tumor-associated angiogenesis is suppressed, it may limit ...
Jan 24, 2018
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In animal experiments, a human-derived glioblastoma significantly regressed when treated with the combination of an experimental enzyme inhibitor and the standard glioblastoma chemotherapy drug, temozolomide.
Jan 23, 2018
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Understanding how cancer cells are able to metastasize—migrate from the primary tumor to distant sites in the body—and developing therapies to inhibit this process are the focus of many laboratories around the country. ...
Dec 15, 2017
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Cancer of the pancreas is a deadly disease, with a median survival time of less than six months. Only one in 20 people with pancreatic cancer survives five years past the diagnosis. The reason is the cancer's insidiousness; ...
Oct 28, 2017
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