Medical research

Scientists identify pathway to curb spread of brain cancer

UT Southwestern researchers have identified a molecular pathway responsible for the spread of glioblastoma to surrounding tissue in the brain, as well as an existing drug that curbed tumor growth in animal models. The findings, ...

Oncology & Cancer

Discovery could lead to better cancer immunotherapy

A type of white blood cell previously known only as a helper in the immune system appears also to be the instigator of the body's defenses against cancerous tumors. The discovery could lead to more effective cancer immunotherapy, ...

Medical research

Working to stop the spread of breast cancer

Michigan State researchers are revealing the molecular workings of how a certain form of metastatic breast cancer spreads to other parts of the body. In doing so, they're creating new opportunities to spot and contain what ...

Oncology & Cancer

Reprogrammed macrophages promote spread of breast cancer

Metastatic breast cancer cells abuse macrophages, a type of immune cell, to promote the settlement of cancer metastases in the lungs. The reprogrammed macrophages stimulate blood vessel cells to secrete a cocktail of metastasis-promoting ...

Medical research

Breast cancer: Why metastasis spreads to the bone

When cancer cells break away from a primary tumor and migrate to other organs, this is called "metastatic cancer." The organs affected by these metastases, however, depend in part on their tissue of origin. In the case of ...

Oncology & Cancer

Tumors change their metabolism to spread more effectively

Cancer cells can disrupt a metabolic pathway that breaks down fats and proteins to boost the levels of a byproduct called methylmalonic acid, thereby driving metastasis, according to research led by scientists at Weill Cornell ...

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