Medical research

Extracellular viscosity linked to cancer spread

New research findings show how higher viscosity, or resistance to flow, of the extracellular fluid that surrounds cells enables cancer cells to migrate more rapidly from a primary tumor to other sites in the body.

Oncology & Cancer

Biosensor detects brain tumors with less than a drop of blood

Despite significant advances, mortality from brain tumors remains high with five-year survival rates of 36%, according to the National Cancer Institute. More accurate diagnoses might improve the situation, but tissue biopsies ...

Medical research

Scientists identify pathway to curb spread of brain cancer

UT Southwestern researchers have identified a molecular pathway responsible for the spread of glioblastoma to surrounding tissue in the brain, as well as an existing drug that curbed tumor growth in animal models. The findings, ...

Oncology & Cancer

Discovery could lead to better cancer immunotherapy

A type of white blood cell previously known only as a helper in the immune system appears also to be the instigator of the body's defenses against cancerous tumors. The discovery could lead to more effective cancer immunotherapy, ...

Medical research

Working to stop the spread of breast cancer

Michigan State researchers are revealing the molecular workings of how a certain form of metastatic breast cancer spreads to other parts of the body. In doing so, they're creating new opportunities to spot and contain what ...

Oncology & Cancer

Reprogrammed macrophages promote spread of breast cancer

Metastatic breast cancer cells abuse macrophages, a type of immune cell, to promote the settlement of cancer metastases in the lungs. The reprogrammed macrophages stimulate blood vessel cells to secrete a cocktail of metastasis-promoting ...

Oncology & Cancer

Tumors change their metabolism to spread more effectively

Cancer cells can disrupt a metabolic pathway that breaks down fats and proteins to boost the levels of a byproduct called methylmalonic acid, thereby driving metastasis, according to research led by scientists at Weill Cornell ...

Oncology & Cancer

DNA nanotubes deliver therapeutics to glioblastoma tumors

Glioblastoma is widely considered the most aggressive brain cancer. Even with treatment, patient survival rates are low, with most living an average of 15–18 months after diagnosis. Because of the highly diverse characteristics ...

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