Genetics

Epigenetic emergency switch improves defense against infections

During infections, the hematopoietic system switches from normal to emergency mode. This improves the defense against pathogens. Scientists at the German Cancer Research Center have now found an epigenetic switch in blood ...

Medical research

New mouse model provides unprecedented look at human immune system

Upon the prick of a finger or scrape of the knee, neutrophils rush to the scene. These white blood cells are the first line of defense against infection in all multicellular organisms. "They are absolutely essential for life," ...

Oncology & Cancer

Rhombic lip implicated in origins of high-risk medulloblastoma

Scientists at St. Jude Children's Research Hospital have discovered which cells give rise to certain high-risk groups of medulloblastoma. The findings will help researchers better understand the biology of the disease, as ...

Oncology & Cancer

How intestinal cancer stem cells evade anti-angiogenic therapy

A team led by Ludwig Lausanne's Tatiana Petrova, Jeremiah Bernier-Latmani and alum Christoph Cisarovsky identified a novel mechanism by which stem cells in intestinal tumors generate new blood vessels and evade anti-angiogenic ...

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