Oncology & Cancer

Immune checkpoint inhibitor endocrine dysfunction explored

(HealthDay)—Patients receiving immune checkpoint inhibitor (ICI) regimens may experience endocrine dysfunction, with increased risk of thyroid dysfunction and hypophysitis for patients on combination therapy, according ...

Oncology & Cancer

Chronic cell death promotes liver cancer

Liver cancer occurs predominantly in patients whose liver has been damaged as a result of chronic disease. Until now, it was not known how these events are linked at the molecular level. An international team of scientists ...

Diseases, Conditions, Syndromes

Trigger for fatty liver in obesity found

Morbid obesity affects the liver: Almost one-third of all adults suffer from chronic fatty liver disease, which can lead to infections and even trigger cancer. Researchers at the University Children's Hospital Zurich and ...

Oncology & Cancer

Combining immunotherapies effective against mouse model of cancer

Rhabdomyosarcoma, a cancer made up of cells that normally develop into skeletal muscles, is the most common soft tissue cancer in children. If it is detected early and localized in certain areas, rhabdomyosarcoma is usually ...

Medical research

The link between protein aggregation and aging

Not only does our way of life determine how long we live but so too does our genetic material. Of particular importance here is a genetic program that is controlled by the insulin receptor. A team of researchers from the ...

Genetics

MicroRNAs protect the precursors of neurons from apoptosis

Programmed cell death is an integral part of embryonic development. Exploring the regulation of the process, Ludwig-Maximilians-Universitaet (LMU) in Munich researchers have shown that so-called microRNAs protect the precursors ...

Immunology

Study identifies new mechanism for antibacterial immunity

The innate immune system serves as a first-line defense, responding to infections almost immediately after a pathogen makes its way into the body. This response is carried out in two major ways: the cell can amplify the message ...

Oncology & Cancer

New treatment for advanced melanoma shows promise

In a study appearing in the April 19, 2016 issue of JAMA, Antoni Ribas, M.D., Ph.D., of the University of California-Los Angeles, and colleagues examined tumor response and overall survival following administration of the ...

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