A prospective study by Wei Zheng, Ph.D., M.D., and colleagues delivers the first direct epidemiological evidence that increased production of a chemical compound called prostaglandin E2 (PGE2), as measured by metabolites ...
Dec 8, 2017
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Pain serves as a warning signal to indicate the intensity and location of damage to the body. In addition to unpleasant sensations, painful events trigger negative emotional responses that may serve to reinforce pain-avoiding ...
Mar 13, 2017
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Research in the laboratory of Rebecca Wingert, the Gallagher Family Associate Professor of Adult Stem Cell Research in the Department of Biological Sciences at the University of Notre Dame, has confirmed the key role of a ...
Dec 21, 2016
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(HealthDay)—The synthetic prostaglandin E1 analogue misoprostol has known severe side effects and should be considered in cases of postpartum hyperthermia, rigors, and tachycardia, according to a case report published in ...
May 11, 2016
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(HealthDay)—Network meta-analysis, which compares multiple treatment options, suggests that prostaglandins are best for decreasing intraocular pressure at three months in primary open angle-glaucoma (POAG), according to ...
Apr 19, 2016
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It's been about a decade since the promise of COX-2 inhibitors—drugs that relieve arthritis pain and inflammation without the gastrointestinal side effects of other painkillers—was tempered by the realization that they ...
Nov 12, 2015
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Fever is a response to inflammation, and is triggered by an onset of the signaling substance prostaglandin. Researchers at Linköping University in Sweden can now see precisely where these substances are produced – a discovery ...
Aug 26, 2014
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A paper in the journal Science about the fertility of roundworms may have implications for everything from captive pandas to infertile couples struggling to conceive.
May 15, 2014
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Harvard stem cell scientists have a new theory for how stem cells decide whether to become liver or pancreatic cells during development. A cell's fate, the researchers found, is determined by the nearby presence of prostaglandin ...
Feb 13, 2014
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Distal renal tubular acidosis (dRTA) develops in response to the loss of acid secretion by α-intercalated cells in the kidney. The inability to remove acid from the body results in low blood potassium levels (hypokalemia), ...
Sep 24, 2013
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