A lysophosphatidic acid receptor 1 (LPAR1) inhibitor, known as Debio-0719, suppresses the development of metastases in mice by inducing cancer cell dormancy, according to a study published August 21 in the Journal of the ...
Aug 21, 2012
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Published in the Advanced Functional Materials, University of Minnesota researcher Hongbo Pang led a cross-institutional study on improving the efficacy of nucleotide-based drugs against prostate cancer and bone metastasis.
Apr 20, 2021
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A new method has been found for identifying therapeutic targets in cancers lacking specific key tumor suppressor genes. The process, which located a genetic site for the most common form of prostate cancer, has potential ...
Feb 6, 2017
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(Medical Xpress)—A cancer therapy that removes malignant cells from a patient's cerebrospinal fluid may soon be available to prevent metastases and decrease complications of cancers involving the brain, according to Penn ...
Jul 30, 2013
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A team of scientists from Sanford Burnham Medical Research Institute (Sanford-Burnham) has found that the loss of a protein called p62 in the cells and tissue surrounding a tumor can enhance the growth and progression of ...
Jul 3, 2014
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Like normal cells, cancer cells require amino acids for growth, maintenance, and cell signaling, and L-type amino acid transporters (LATs) are the delivery vehicles that supply them. Metastatic, castration-resistant prostate ...
Sep 19, 2013
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In a genome-wide analysis of 13 metastatic prostate cancers, scientists at the Johns Hopkins Kimmel Cancer Center found consistent epigenetic "signatures" across all metastatic tumors in each patient. The discovery of the ...
Jan 23, 2013
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Metal detection has helped mining companies strike gold and airport security identify passengers who are a potential threat. Now USC scientists have pushed its use into another realm: studying cancer.
Feb 27, 2018
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Actinium-targeted alpha radiotherapy is a promising approach for treating metastatic cancers, including prostate cancer. This approach requires doctors to obtain images of the radiotherapy agent as it moves to tumors, a process ...
Aug 28, 2023
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Cabozantinib, a drug already used to treat patients with certain types of thyroid or kidney cancer, was able to eradicate invasive prostate cancers in mice by causing tumor cells to secrete factors that entice neutrophils ...
Mar 8, 2017
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