Immunology

Identifying a key player in gut defense development

Scientists have identified a protein critical to the immune system development and antibody production in mice, which could contribute to understanding the gut defense mechanism in infants.

Oncology & Cancer

New gene potentially involved in metastasis identified

Cancers that display a specific combination of sugars called T-antigens are more likely to spread through the body and kill a patient. However, scientists do not understand what regulates the appearance of T-antigen in cancer ...

Oncology & Cancer

Why we're looking for cancer clues in urine

The human immune system is actually quite good at killing cancer cells. In fact, we believe it does so quite frequently. People who have AIDS or have had an organ transplant have suppressed immune systems and go on to develop ...

Immunology

Countering atopic dermatitis immune reactions

Human leukocyte antigen (HLA)-G is a protein that interacts with specific cell receptors to inhibit immune responses. The protein is best known for its role in protecting the fetus from attack by its mother's immune system. ...

Arthritis & Rheumatism

ACR: Contraception choice may affect RA-related autoantibodies

(HealthDay)—For women at increased risk of rheumatoid arthritis (RA), choice of contraceptive may affect serum autoantibodies to citrullinated protein antigens (ACPA) positivity, according to a study presented at the annual ...

Oncology & Cancer

Modified immune cells seek and destroy melanoma

In this issue of the Journal of Clinical Investigation, researchers led by Scott Pruitt at Duke University and Merck Research Laboratories report on a human clinical trial in which modified dendritic cells, a component of ...

Medical research

Research suggests origins of key cells in the thymus

Medullary thymic epithelial cells (mTECs) allow the thymus to ensure that the body's T cells are able to distinguish between potentially harmful foreign antigens and those that are produced by the body itself. A Swiss-Japanese ...

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