Alzheimer's disease develops over decades. It begins with a fatal chain reaction in which masses of misfolded beta-amyloid proteins are produced that in the end literally flood the brain. Researchers including Mathias Jucker ...
Nov 17, 2020
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Researchers at the Paul Scherrer Institute, together with colleagues from the pharmaceutical company F. Hoffmann-La Roche AG, have taken an important step toward the development of an agent against the metastasis of certain ...
Aug 22, 2019
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Researchers at the University of Toronto have uncovered an immune mechanism by which host cells combat bacterial infection, and at the same time found that a protein crucial to that process can sense and respond to misfolded ...
Jul 8, 2019
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By replacing or replenishing injured tissue with biomimetic structures, scientists can help initiate stem cell-driven repair cascades throughout the body. Insights from an A*STAR-led study of the interactions between bone ...
Mar 18, 2019
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A naturally occurring human enzyme -called cyclophilin 40 or CyP40- can unravel protein aggregates that contribute to both Alzheimer's disease and Parkinson's disease, according to a study publishing June 27 in the open access ...
Jun 27, 2017
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Malignant melanoma is one of the most common and dangerous types of cancer. Researchers at Friedrich-Alexander Universität Erlangen-Nürnberg (FAU) investigated how and why brown pigmented moles turn into malignant melanoma ...
May 23, 2017
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New research presented at this year's European Congress on Obesity (ECO) in Porto, Portugal (17-20 May) shows the obese people have higher levels of a protein called survivin, which protects fat-containing adipocyte cells ...
May 18, 2017
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(HealthDay)—Both retinol and retinoic acid have beneficial effects on cellular and molecular properties of the epidermis and dermis, according to a study published online Nov. 18 in the Journal of Cosmetic Dermatology.
Nov 25, 2015
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Recently, a grassroots effort initiated by families and clinicians led to the discovery of a human genetic disorder with severe consequences that is linked to a mutation in the human NGLY1 gene. In a big step towards understanding ...
Jan 19, 2015
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Researchers at Johns Hopkins have uncovered a protein switch that can either increase or decrease memory-building activity in brain cells, depending on the signals it detects. Its dual role means the protein is key to understanding ...
Aug 13, 2013
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