Medical research

Proxidrugs in the fight against pathogenic proteins

Cells have an efficient waste disposal system. Proxidrugs utilize this system as part of new treatments for cancer, infections and Alzheimer's disease. Scientists at the Fraunhofer Institute for Translational Medicine and ...

Diseases, Conditions, Syndromes

Enhancing the effect of protein-based COVID-19 vaccines

Ironically, some vaccines need their own "boosters." Adding an ingredient called an adjuvant can help vaccines elicit a more robust immune response, better training the body to fight a pathogen. In a new study in ACS Infectious ...

Genetics

Why some people suffer more from COVID-19 than others

A large number of people are currently contracting COVID-19. Fortunately, most of them are experiencing only mild symptoms, largely thanks to the high vaccination rate. However, in some individuals the disease takes a much ...

Medications

A 'smashing' solution for cancer therapy

Sometimes too much of a good thing is not good at all. Inhibiting the function of the PD-1 protein, which blocks immune function, has shown high therapeutic efficacy in cancer immunotherapy. However, when this function is ...

Medical research

Scientists discover clue to stopping Lassa virus infection

Lassa fever is a viral illness that is far too common in West Africa. Although it can have a mortality rate of 15% in severe cases, up to 90% in pregnant women, and causes deafness in a quarter of survivors, there is no vaccine ...

Diseases, Conditions, Syndromes

Examining COVID-19 and its many sublineages

As new omicron subvariants of COVID-19 continue to sweep across the United States, researchers at the University of Missouri have identified specific mutations within the virus' spike protein that help omicron subvariants ...

Medical research

A new treatment approach for cystic fibrosis

Antisense oligonucleotides, or ASOs, are molecules that can be used to control protein levels in cells. Cold Spring Harbor Laboratory Professor Adrian Krainer leveraged ASO technology to develop the first FDA-approved treatment ...

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