In animals, a process of programmed cell death called apoptosis ensures cells die when they should. An opposing force, governed by inhibitor of apoptosis proteins (IAPs), guards against excessive cell death. Together these ...
Feb 9, 2023
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A drug which is used to treat the common eye disease glaucoma may have potential as a treatment for Alzheimer's disease, according to scientists at UCL.
Dec 9, 2016
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A team of researchers from the University of Iowa, University Medical Center Utrecht and Vertex Pharmaceuticals Incorporated, reports that earlier administration of a drug already given to patients with a rare form of cystic ...
Physicians have used the drug metformin to treat type 2 diabetes for more than half a century, but despite its prevalence, researchers have lacked a clear understanding of how it works. Now, Yale researchers have elucidated ...
Mar 3, 2022
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Low levels of the blood protein renalase predict poor outcomes in patients with COVID-19, Yale researchers report. They are planning to ask for expedited approval from the U.S. Food and Drug Administration to investigate ...
Jun 12, 2020
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In recent years, a powerful suite of drugs known as kinase inhibitors have been developed to treat cancer and other diseases. Primary targets of such drugs include a family of receptor tyrosine kinases (RTKs) which protrude ...
Feb 5, 2018
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A vaccine developed by Duke Cancer Institute researchers has shown early promise in targeting the HER2 protein that fuels a deadly form of breast cancer.
Mar 12, 2019
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University of Maryland School of Medicine (UMSOM) researchers have identified the most toxic proteins made by SARS-COV-2—the virus that causes COVID-19—and then used an FDA-approved cancer drug to blunt the viral protein's ...
Mar 26, 2021
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(Medical Xpress) -- A team of Melbourne scientists has discovered a new type of cell in the immune system. Their findings could ultimately lead to the development of novel drugs that strengthen the immune response against ...
Jun 14, 2011
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Mutations in a vital class of regulatory molecules are an underappreciated cause of cancer because they impair the function of "G" proteins, a versatile and vast family of signaling switches that underlie innumerable biological ...
