Medications

Cause of heart damage from cancer drugs identified

Modern drugs can be very effective at treating cancer and have led to greatly improved survival rates. However, some cancer treatments can cause damage to the heart, or cardiotoxicity. This damage can present in a range of ...

Alzheimer's disease & dementia

Progress on early detection of Alzheimer's disease

Inside the body, some seemingly harmless proteins have sinister potential. In the case of Alzheimer's disease, the amyloid-beta (Aβ) protein, which is vital for brain growth, can become tainted and destroy cells, which leads ...

Medical research

The role of metabolic signaling in preventing atrial fibrillation

Research from the Yale School of Medicine indicates that a protein kinase that is a master regulator of cell metabolism is critical to preventing atrial fibrillation. The research appeared April 22 in the journal JCI Insight.

Medical research

Unexpected protein could play role in common brain disorder

Scientists have known for years that amyloid fibrils—fibrous, ropelike structures formed by closely linked protein molecules—are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play ...

Psychology & Psychiatry

New study reveals possible causes of psychiatric disorders

In a new study, scientists from Forschungszentrum Jülich and Heinrich Heine University Düsseldorf (HHU) have demonstrated for the first time that improper protein conformation is linked to the development of certain psychiatric ...

Alzheimer's disease & dementia

Novel Alzheimer's disease amyloid β polymorph revealed

Alzheimer's disease (AD) is a neurological condition leading to dementia that worsens with age as patients exhibit cognitive, memory, and psychological deficits. While current therapies focus on relieving these symptoms to ...

Oncology & Cancer

An amyloid link between Parkinson's disease and melanoma

On the surface, Parkinson's disease—a neurodegenerative disorder—and melanoma—a type of skin cancer—do not appear to have much in common. However, for nearly 50 years, doctors have recognized that Parkinson's disease ...

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