PGK1, a glycolytic enzyme, has been found to play a role in coordinating cellular processes crucial to cancer metabolism and brain tumor formation, according to results published in today's online issue of Molecular Cell. ...
Mar 3, 2016
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An international public-private research consortium has identified and validated a cellular role of a primary Parkinson's disease drug target, the LRRK2 kinase. This important finding, published in the online, open-access ...
Jan 28, 2016
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A group of protein kinases have been found to play an important role in embryo development and may even be a potential cancer drug target, says research led by Queen Mary University of London (QMUL) and the Francis Crick ...
Jan 7, 2016
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In their recent study, Thomas Leonard and his group at the Max F. Perutz Laboratories (MFPL) of the University of Vienna and the Medical University of Vienna have shown that the cellular activity of the enzyme ROCK is controlled ...
Dec 10, 2015
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EMBL-EBI researchers have developed a new computational method to study biological signalling networks in healthy and cancer cells.
Sep 10, 2015
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Protein Kinase C (PKC) is a family of enzymes that controls the activity of other proteins in a cell by attaching chemical tags. That simple act helps determine cell survival or death. When it goes awry, a number of diseases ...
Aug 13, 2015
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A new compound developed at the University of Toronto Scarborough could play an important role in developing cheaper anti-cancer drugs.
Feb 25, 2015
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Macrophages are best known for their Pac Man-like ability to gobble up cellular debris and pathogens in order to thwart infection. A new study in The Journal of Cell Biology describes how these immune cells also help resolve ...
Dec 8, 2014
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A newly identified signaling pathway that stimulates glucose uptake in brown fat cells might be useful for treating type 2 diabetes and obesity, according to a study in The Journal of Cell Biology.
Nov 10, 2014
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Scientists have shown how to better identify and measure vital molecules that control cell behaviour – paving the way for improved tools for diagnosis, prediction and monitoring of cancer.
Aug 26, 2014
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