Medical research

AQAMAN takes aim at rare neurodegenerative diseases

A synthetic small molecule compound called AQAMAN can prevent and even reverse harmful protein build-up in neurons that is associated with several rare neurodegenerative disorders, including polyglutamine (or polyQ) diseases.

Genetics

Gene that causes atrial fibrillation discovered

Genetic studies spanning three generations of a Persian Jewish family by researchers at Ben-Gurion University of the Negev (BGU) have identified a gene that causes nighttime atrial fibrillation (AFib).

Alzheimer's disease & dementia

How an Alzheimer's-related protein forms plaques

Neurological diseases such as Alzheimer's disease are characterised by aggregates of protein in the brain. The connection of these aggregates to the disease itself is unclear. Martina Huber, Enrico Zurlo and colleagues published ...

Genetics

Potential entry points for Huntington's disease drug discovery

Huntington's disease (HD) is one of the four major neurodegenerative diseases that have been most extensively studied. The clinical symptoms include uncontrolled dancing-mimicking behavior (chorea), as well as cognitive deficiency ...

Medical research

Figuring out Alzheimer's

One of the tasks of scientists' work is to explain how the world functions. Their research ideas may often seem unrealistic but, as it turns out, their research may truly help a great many of us.

Neuroscience

Tau-mediated RNA splicing errors linked to Alzheimer's disease

A collaborative study published today in the journal Cell Reports provides evidence for a new molecular cause for neurodegeneration in Alzheimer's disease. The study, led by researchers at Baylor College of Medicine and the ...

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