Medical research

Receptors under flow: Mechanosensitive GPCRs

An LMU team has clarified how a receptor which is involved in the regulation of vital physiological processes senses the mechanical forces that act on blood vessels. The findings could suggest new therapies for diseases of ...

Oncology & Cancer

Tracking genes to fight breast cancer

Ph.D. student Esmee Koedoot studied the underlying processes responsible for metastases in a dangerous type of breast cancer. She hopes to find new possibilities to fight the disease. In December 2019 she obtained her doctorate ...

Neuroscience

Study reveals mysteries of critical brain receptor complex

Glutamate receptors in the brain called AMPARs are critical for synaptic plasticity, learning and memory. Poorly functioning AMPARs have been linked to a wide range of neurological and psychiatric disorders including seizures, ...

Medical research

Activation of opioid receptor uncovered

Together with colleagues from Shanghai, Brussels, Canada and the USA, researchers from the University of Bonn have uncovered the binding mechanism of an important pain receptor. The results facilitate the development of new ...

Diabetes

Helper protein worsens diabetic eye disease

In a recent study using mice, lab-grown human retinal cells and patient samples, Johns Hopkins Medicine scientists say they found evidence of a new pathway that may contribute to degeneration of the light sensitive tissue ...

Oncology & Cancer

Protein decoy stymies lung cancer growth in mice, study finds

Scientists at Stanford and UC-San Francisco have developed an experimental drug that targets a currently untreatable type of lung cancer responsible for generating roughly 500,000 newly diagnosed cases worldwide each year.

Oncology & Cancer

Gene-targeted cancer drugs, slow release overcome resistance

Biomedical engineers at Duke University have developed a method to address failures in a promising anti-cancer drug, bringing together tools from genome engineering, protein engineering and biomaterials science to improve ...

Diseases, Conditions, Syndromes

Talking receptors may affect relaxin at work

Fibrosis, the damaging build-up of hardened or scarred tissue in the body, is a hallmark of various diseases and can lead to the dysfunction and failure of organs such as the heart and kidney. Fibrosis-related diseases in ...

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