Obesity not only increases the risk of metabolic syndrome-related diseases, such as diabetes, fatty liver, and atherosclerosis, but also remarkably impacts seemingly unrelated conditions, such as cancer, psychiatric disorders, ...
Aug 24, 2023
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10
Disruption of the circadian clocks that keep the body and its cells entrained to the 24-hour day-night cycle plays a critical role in weight gain, according to a pair of studies by Weill Cornell Medicine investigators.
Aug 8, 2022
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Researchers have identified amyloid beta (Aβ) detected in blood to originate from peripheral tissues, and that the peptide acts on pancreaticβ-cells to suppress insulin secretion, thereby regulating blood glucose levels. ...
Mar 15, 2022
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A study in mice—led by researchers at Washington University School of Medicine in St. Louis—shows that a new class of compounds the scientists developed can improve multiple aspects of metabolic syndrome. An increasingly ...
Feb 11, 2022
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Existing and emerging cancer drugs could be repurposed as therapies to be tested in clinical trials for people at genetic risk of Alzheimer's disease, according to a new study published in Science Advances. Research combining ...
Nov 10, 2021
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Researchers from Tokyo Medical and Dental University (TMDU) have found that the secretion of uromodulin protein into urine can be induced by treatments that may protect against urinary tract infections and kidney stones, ...
Jun 17, 2021
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By blocking a protein, VDAC1, in the insulin-producing beta cells, it is possible to restore their normal function in case of type 2 diabetes. In preclinical experiments, the researchers behind a new study have also shown ...
Oct 8, 2018
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A study published online in The FASEB Journal demonstrated that a protein complex (Gbeta5-RGS) commonly known for halting cellular functions may actually stimulate insulin secretion in pancreatic cells. This discovery offers ...
Jul 10, 2017
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A new study by University of Kentucky Markey Cancer Center researchers shows that chloroquine – a drug currently used to treat malaria – may be useful in treating patients with metastatic cancers.
Jan 11, 2017
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A group of researchers identified a molecular machinery by which autophagy mediates secretion. These results underscore an important role of autophagy other than degradation, and will bring us to future translational research ...
Jan 10, 2017
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