Diseases, Conditions, Syndromes

Hepatitis B virus promotes oncogenesis through microRNA modulation

Viruses prompt oncogenic transformation by genetically altering infected cells. Several recent studies have demonstrated that viruses alter the expression of microRNAs, non-coding RNA molecules that can block the expression ...

Medical research

How to enable light to switch on and off therapeutic antibodies

When antigens such as a virus or bacteria invade our body, the immune system springs into action: it creates antibodies that stick to the antigens so that they can identify and destroy the intruders. Did you know that these ...

Diseases, Conditions, Syndromes

Scientists identify possible drug target for acute pancreatitis

Scientists from the Universities of Illinois and California have found that the inflammatory protein interleukin-6 (IL-6) plays a pivotal role in the duration of acute pancreatitis in animal models with this condition. Their ...

Neuroscience

Revealing the intra-cellular mechanism underlying ALS

A new study uncovering the mechanism behind amyotrophic lateral sclerosis (ALS or also Lou Gehrig's disease) has brought doctors a step closer to identifying drug targets for the malady. Tsukasa Uchida and collaborators at ...

Oncology & Cancer

Alternative target for breast cancer drugs

Scientists have identified higher levels of a receptor protein found on the surface of human breast tumour cells that may serve as a new drug target for the treatment of breast cancer. The results, which are published today ...

Oncology & Cancer

Researchers show Myc protein is cancer's 'volume control'

(Medical Xpress)—A protein called Myc, commonly found at high levels inside cancer cells, fuels the disease by allowing cells to override their in-built self-destruct mechanisms, according to two new studies by US scientists.

Medical research

A tool to interrogate a new class of drugs

In 2014, the European Medicines Agency approved the drug Tecfidera for the treatment of relapsing multiple sclerosis, a neurodegenerative disease that affects millions of people worldwide. In multiple sclerosis, inflammation ...

Oncology & Cancer

The factor that could influence future breast cancer treatment

Australian scientists have shown in the laboratory how a 'transcription factor' causes breast cancer cells to develop an aggressive subtype that lacks sensitivity to estrogen and does not respond to known anti-estrogen therapies. ...

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