During the pre-clinical stages of Alzheimer's disease, i.e. when subtle changes are taking place in the brain but no cognitive symptoms can be observed, the cortex presents a state of transient hyperexcitability. To date, ...
Jan 25, 2021
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In three recent publications in Molecular Psychiatry, Brain and JAMA Neurology researchers from the University of Gothenburg provide convincing evidence that an in-house developed blood test for Alzheimer's disease can detect ...
Jan 13, 2021
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(HealthDay)—Some older folks are still sharp as tacks and dementia-free well into their 80s and beyond. Now German researchers have uncovered a possible reason why: Their genes may help them fend off protein build-up in ...
Dec 21, 2020
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Research into Alzheimer's disease has long focused on understanding the role of two key proteins, beta amyloid and the tau protein. Found in tangles in patients' brain tissue, a pathological form of the tau protein contributes ...
Nov 19, 2020
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Alzheimer's disease is the most common dementia worldwide and it is characterized by learning impairment, memory loss, disorientation and anxiety, among other behavioral and psychological symptoms. Since Alois Alzheimer described ...
Nov 16, 2020
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In Alzheimer's disease, impaired blood flow to brain regions coincides with tau protein buildup. This relationship strengthens as cognition declines, according to new research published in JNeurosci.
Oct 12, 2020
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In a healthy brain, the multistep waste clearance process known as autophagy routinely removes and degrades damaged cell components—including malformed proteins like tau and toxic mitochondria. This cellular debris would ...
Oct 12, 2020
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Accumulation of assembled tau protein in the central nervous system is characteristic of Alzheimer's disease and several other neurodegenerative diseases, called tauopathies. Recent studies have revealed that propagation ...
Sep 23, 2020
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A genetic variation in some people may be associated with cognitive decline that can't be explained by deposits of two key proteins associated with Alzheimer's disease, amyloid β and tau, according to a study published in ...
Sep 16, 2020
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Super-agers, or individuals whose cognitive skills are above the norm even at an advanced age, have been found to have increased resistance to tau and amyloid proteins, according to research presented at the Society of Nuclear ...
Jul 15, 2020
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