Genetics

Understanding the effects of genes on human traits

Recent technological developments in genomics have revealed a large number of genetic influences on common complex diseases, such as diabetes, asthma, cancer or schizophrenia. However, discovering a genetic variant predisposing ...

Medical research

Silent RNAs express themselves in ALS disease

RNA molecules, used by cells to make proteins, are generally thought to be "silent" when stowed in cytoplasmic granules. But a protein mutated in some ALS patients forms granules that permit translation of stored RNAs, according ...

Oncology & Cancer

Thwarting protein production slows cancer cells' malignant march

Protein production or translation is tightly coupled to a highly conserved stress response that cancer cells rely on for survival and proliferation, according to Whitehead Institute researchers. In mouse models of cancer, ...

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