Immunology

How regulatory T cells halt aberrant, self-reactive T cells

New research findings show in detail how self-reactive T cells—white blood cells that mistakenly attack healthy instead of infected cells, thereby causing an autoimmune or an inflammatory response—are held in check by ...

Oncology & Cancer

Structural insights reveal how SPOP protein contributes to cancer

SPOP is the most mutated protein in prostate cancer and plays a role in endometrial, uterine and other cancers. Despite this importance, how SPOP mutations drive cancer has been incompletely understood. Scientists at St. ...

HIV & AIDS

Scientists find potential cellular target for HIV therapies

Researchers at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology have discovered a protein that appears to play a key role in helping HIV replicate in human immune cells, providing more clues ...

Medical research

Stopping a rare childhood cancer in its tracks

Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered a new drug target for Ewing sarcoma, a rare kind of cancer usually diagnosed in children and young adults. Their experiments show that the cells causing this ...

Alzheimer's disease & dementia

Scientists developing early Alzheimer's disease detection sensor

Researchers with the SFU Nanodevice Fabrication Group are developing a new biosensor that can be used to screen for Alzheimer's disease and other diseases. An overview of their work has been recently published in the journal ...

Alzheimer's disease & dementia

Neuroscientists solve mysteries about leading biomarker for Alzheimer's

University of Virginia neuroscientists have revealed how a toxic form of tau protein, notorious for forming tangles in the brains of people with Alzheimer's disease and several other neurodegenerative disorders, spreads through ...

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