Diseases, Conditions, Syndromes

PPI-gastric cancer link remains after H. pylori eradication

(HealthDay)—Long-term proton pump inhibitor (PPI) use is associated with increased risk of gastric cancer (GC) even after Helicobacter pylori (HP) eradication therapy, according to a study published online Oct. 31 in Gut.

Oncology & Cancer

ASCO: antibiotics may have negative impact in renal cancer

(HealthDay)—For patients with metastatic renal cell carcinoma (mRCC) receiving immune checkpoint inhibitors, treatment with broad-spectrum antibiotics (ATBs) can reduce progression-free survival, according to research presented ...

Medications

Many physicians still prescribe controversial drug combination

Safety concerns of the concomitant use of clopidogrel with the proton pump inhibitors (PPIs) omeprazole or esomeprazole were published in May 2009 and February 2010 by European regulatory agencies. After the last publication, ...

Medications

Two pancreatic-enzyme products approved

(HealthDay) -- Two drugs that supplement the digestion-aiding actions of pancreatic enzymes have been approved by the U.S. Food and Drug Administration, the agency said Thursday in a news release.

Diseases, Conditions, Syndromes

Upper endoscopy is overused in patients with heartburn

Heartburn is one of the most common reasons for people to see a doctor, and some physicians often use upper endoscopy to diagnose and manage gastroesophageal reflux disease (GERD). But most patients do not require the procedure ...

Diseases, Conditions, Syndromes

Proton pump inhibitors linked to disruption of gut microbiome

(HealthDay)—Proton pump inhibitors may disrupt the microbiome of the digestive system, leading to infections and other complications, according to a small new study published online Nov. 25 in Microbiome.

Diseases, Conditions, Syndromes

Gastric acid suppressants linked to hospitalization

New research has found a link between popular heartburn drugs and an increase in the risk of infectious gastroenteritis—an illness that results in 13.1 million lost days of work in Australia a year.

Diseases, Conditions, Syndromes

Diuretics in proton pump inhibitor-associated hypomagnesemia

Proton pump inhibitor (PPI) therapy is associated with hospitalization for hypomagnesemia, particularly among patients also receiving diuretics, according to research published this week in PLOS Medicine. The study, conducted ...

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