Immunology

Females found to itch less than males

Among the many reasons men may have for envying women, at least when it comes to skin inflammation, is that women have a significantly lower incidence of severe psoriasis. However, the underlying reason for the sex differences ...

Diseases, Conditions, Syndromes

Scientists identify sensor underlying mechanical itch stimulus

Scientists at Scripps Research Institute have identified a protein in sensory nerves that works as a key detector of itch—specifically the "mechanical" itch stimulus of crawling insects, wool fibers, or other irritating ...

Inflammatory disorders

Predictors of diagnostic delay in psoriasis identified

Diagnostic delay is common for patients with psoriasis and is increased for men and with psoriasis in specific areas, according to a study recently published online in the British Journal of Dermatology.

Obstetrics & gynaecology

Risk for ectopic pregnancy increased for women with psoriasis

Women with psoriasis have a significantly increased risk for ectopic pregnancy (EP), which is highest for those with moderate-to-severe psoriasis, according to a study published in the June issue of JAAD International.

Inflammatory disorders

Lifestyle factors are predictive of incident psoriasis

Lifestyle factors are predictive of the risk for incident psoriasis, regardless of genetic risk, according to a study published online April 12 in the Journal of the American Academy of Dermatology.

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Psoriasis

Psoriasis (pronounced /səˈraɪəsɪs/) is a chronic, non-contagious autoimmune disease which affects the skin and joints. It commonly causes red scaly patches to appear on the skin. The scaly patches caused by psoriasis, called psoriatic plaques, are areas of inflammation and excessive skin production. Skin rapidly accumulates at these sites and takes on a silvery-white appearance. Plaques frequently occur on the skin of the elbows and knees, but can affect any area including the scalp and genitals. In contrast to eczema, psoriasis is more likely to be found on the extensor aspect of the joint.

The disorder is a chronic recurring condition which varies in severity from minor localized patches to complete body coverage. Fingernails and toenails are frequently affected (psoriatic nail dystrophy) and can be seen as an isolated finding. Psoriasis can also cause inflammation of the joints, which is known as psoriatic arthritis. Ten to fifteen percent of people with psoriasis have psoriatic arthritis.

The cause of psoriasis is not known, but it is believed to have a genetic component. Factors that may aggravate psoriasis include stress, withdrawal of systemic corticosteroid, excessive alcohol consumption, and smoking. There are many treatments available, but because of its chronic recurrent nature psoriasis is a challenge to treat.

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