Diseases, Conditions, Syndromes

Gene study helps understand pulmonary fibrosis

A new study looking at the genomes of more than 1,500 patients with idiopathic pulmonary fibrosis, a rare and devastating lung disease, found multiple genetic associations with the disease, including one gene variant that ...

Medical research

Mast cells have critical role in initializing pulmonary fibrosis

Pulmonary fibrosis is a chronic, deadly disease that affects five million people worldwide. It is irreversible, its cause is poorly understood, and it has a median survival of only about 3 years. A new study that implicates ...

Other

First 'breathing lung' transplant on East Coast using OCS lung

UPMC surgeons have performed a "breathing lung" transplant using a portable machine that provides a constant supply of blood and nutrients to the donor organs, which doctors say has the potential to keep them healthier and ...

Medical research

Pulmonary fibrosis: Between a ROCK and a hard place

Pulmonary fibrosis is a scarring or thickening of the lungs that causes shortness of breath, a dry cough, fatigue, chest discomfort, weight loss, a decrease in the ability of the lungs to transmit oxygen to the blood stream, ...

Surgery

UCLA performs first 'breathing lung' transplant in US

First there was the "heart in a box," a revolutionary experimental technology that allows donor hearts to be delivered to transplant recipients warm and beating rather than frozen in an ice cooler.

Medical research

Researchers implicate well-known protein in fibrosis

An international multi-disciplinary research team led by Northwestern Medicine scientists has uncovered a new role for the protein toll-like receptor 4 (TLR4) in the development of tissue fibrosis, or scarring.

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