Diseases, Conditions, Syndromes

Review examines efficacy of PPI Tx for esophageal eosinophilia

(HealthDay)—About half of patients with symptomatic esophageal eosinophilia have clinicohistologic remission with proton pump inhibitor (PPI) therapy, according to a review published in the January issue of Clinical Gastroenterology ...

Medications

Acid reflux drugs linked to increased fracture risk in kids

Proton pump inhibitors—a widely used class of drugs used to treat acid reflux and related symptoms—may lead to an increased risk of fractures in children and adolescents, reports a study in the Journal of Pediatric Gastroenterology ...

Diseases, Conditions, Syndromes

PPI-gastric cancer link remains after H. pylori eradication

(HealthDay)—Long-term proton pump inhibitor (PPI) use is associated with increased risk of gastric cancer (GC) even after Helicobacter pylori (HP) eradication therapy, according to a study published online Oct. 31 in Gut.

Oncology & Cancer

ASCO: antibiotics may have negative impact in renal cancer

(HealthDay)—For patients with metastatic renal cell carcinoma (mRCC) receiving immune checkpoint inhibitors, treatment with broad-spectrum antibiotics (ATBs) can reduce progression-free survival, according to research presented ...

Medications

Many physicians still prescribe controversial drug combination

Safety concerns of the concomitant use of clopidogrel with the proton pump inhibitors (PPIs) omeprazole or esomeprazole were published in May 2009 and February 2010 by European regulatory agencies. After the last publication, ...

Diseases, Conditions, Syndromes

Upper endoscopy is overused in patients with heartburn

Heartburn is one of the most common reasons for people to see a doctor, and some physicians often use upper endoscopy to diagnose and manage gastroesophageal reflux disease (GERD). But most patients do not require the procedure ...

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