Blood cancer patients, especially when they relapse, have a poor prognosis, and generally do not survive very long. The last five years have seen success in treating these patients with Chimeric Antigen Receptor (CAR) T-cells—a ...
Feb 24, 2023
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Proteins that play key roles in the timing of cell division also moonlight in regulating blood sugar levels, UT Southwestern Medical Center researchers have found.
Jun 30, 2016
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Scientists know that activation of growth factor receptors like epidermal growth factor receptors (EGFR) promote tumor progression in many types of cancer.
Aug 17, 2015
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A new study led by investigators at the Stanford University School of Medicine has implicated the blocking of endocannabinoids—signaling substances that are the brain's internal versions of the psychoactive chemicals in ...
Jun 18, 2014
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SORLA is a protein that influences the balance of metabolic processes in adipose tissue, a particular form of fat. Too much of it makes fat cells overly sensitive to insulin, which leads them to break down less fat. SORLA ...
Jun 21, 2016
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Phospholipids - fat molecules that form the membranes found around cells - make up almost half of the dry weight of cells, but when it comes to autoimmune diseases, their role has largely been overlooked. Recent research ...
Oct 20, 2017
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Chronic bowel inflammation is based on an excessive or misdirected inflammatory reaction. Experts assume that the immune system also reacts incorrectly to microorganisms in the intestine that do not cause an inflammatory ...
Sep 26, 2023
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New research uncovers how a sticky protein called fibronectin promotes the activity of estrogen in breast cancer cells. The study, "Fibronectin rescues estrogen receptor α from lysosomal degradation in breast cancer cells," ...
Jul 6, 2018
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Studying the cellular metabolism of prostate cancer, a team of Duke Health-led researchers identified a key reason hormone therapies eventually fail, while also laying out a way to bypass the problem using an entirely new ...
Mar 22, 2021
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A patient with relapsed T cell leukaemia has been given base-edited T-cells in a world-first use of a base-edited cell therapy, in a 'bench-to-bedside' collaboration between UCL and Great Ormond Street Hospital for Children ...
Dec 11, 2022
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