Gene expression is a highly regulated sequence with many players, one being the estrogen receptor-α (ER), which moves this process along by responding to hormones produced by the endocrine system. When something disrupts ...
Nov 12, 2021
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The androgen receptor is the primary driver of the initiation and growth of prostate cancer, the second-leading cause of death in men. Looking to have a better understanding of how the androgen receptor works in cancer, researchers ...
Jul 14, 2020
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Despite many developments in the diagnosis and treatment of gastric cancer, it continues to be an important public health problem. Therefore, besides classical methods, new biomolecules are needed to facilitate the prediction ...
Jul 13, 2020
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Investigators have identified the specific genes that become overactive as a result of nerve cell infection with Japanese encephalitis virus. The genes activate cell receptors and signaling proteins that attract immune cells ...
Jan 13, 2020
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Indiana University researchers have discovered that a chemical compound found in essential oils improves the healing process in mice when it is topically applied to a skin wound—a finding that could lead to improved treatments ...
Dec 18, 2019
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Researchers at the Bellvitge Biomedical Research Institute (IDIBELL) have published a study in Molecular Cancer Research in which they identify methylation patterns associated with different subtypes of breast cancer, and ...
Jul 19, 2019
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Researchers at Boston University School of Medicine (BUSM) have discovered that blocking a specific protein, may be a promising strategy to prevent the spread of castration-resistant prostate cancer (CRPC).
May 20, 2019
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Aire expression in the thymus contributes to immune tolerance by eliminating auto-reactive T cells; insufficient elimination causes autoimmune disorders. The Aire gene was thought to be expressed only in the thymus, but recently, ...
Apr 11, 2019
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(HealthDay)—Individuals with Alzheimer's disease (AD) have abnormalities and reductions in gene expression in the parahippocampal gyri that map to genes associated with the insulin receptor signaling pathway (IRSP), according ...
Nov 5, 2018
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In most cases of prostate cancer, tumor cell growth is stimulated by the action of male hormones, or androgens, such as testosterone and dihydrotestosterone (DHT). For this to happen, these hormones have to bind to androgen ...
Jul 19, 2018
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