Genetics

Research reveals how estrogen regulates gene expression

Estrogen hormones regulate gene expression. They achieve this by first binding to estrogen receptor in the cell nucleus, which triggers the recruitment of different molecules called coactivators in specific order. In a study ...

Oncology & Cancer

New study identifies essential genes for cancer immunotherapy

A new study identifies genes that are necessary in cancer cells for immunotherapy to work, addressing the problem of why some tumors don't respond to immunotherapy or respond initially but then stop as tumor cells develop ...

Medical research

Researchers gain insights to redirect leading HIV cure strategy

Research at the University of Illinois at Urbana-Champaign has provided the first evidence that viruses and hosts share highly similar regulatory sequences in their promoters—the initiation sequences of human genes that ...

Medical research

New approach makes cells resistant to HIV

Scientists at The Scripps Research Institute (TSRI) have found a way to tether HIV-fighting antibodies to immune cells, creating a cell population resistant to the virus. Their experiments under lab conditions show that these ...

Psychology & Psychiatry

OCD-like behavior linked to genetic mutation

A new Northwestern Medicine study found evidence suggesting how neural dysfunction in a certain region of the brain can lead to obsessive and repetitive behaviors much like obsessive-compulsive disorder (OCD).

Sleep disorders

Genetic cause for shift work fatigue discovered

Some people adapt easily to shift work, but not everyone can handle constant disruptions to their daily rhythm. Finnish researchers have now found that a melatonin receptor gene influences tolerance to shift work.

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