The RIG-I like receptors (RLRs) are intracellular enzyme sentries that detect viral infection and initiate a first line of antiviral defense. The cellular molecules that activate RLRs in vivo are not clear.
Dec 14, 2018
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Tumors usually grow exclusively from where their cell of origin derives. In humans, apart from some rare cases like the accidental transmission through a cut during surgery, there are no reports of contagious cancer cells. ...
Jan 14, 2019
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Researchers at the University of Montreal's Sainte-Justine Hospital have identified how neural cells like those in our bodies are able to build up resistance to opioid pain drugs within hours. Humans have known about the ...
Apr 3, 2012
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Iron overload is a common condition affecting millions of people worldwide. Excess iron in the body is toxic, and deposits can cause damage to the liver, heart and other organs. Current treatments, researchers say, are not ...
Nov 1, 2011
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Regulatory T cells, which are part of the body's immune system, downregulate the activity of other immune cells, thus preventing the development of autoimmune diseases or allergies. Scientists at the German Cancer Research ...
Dec 21, 2011
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In the developing brain, special proteins that act like molecular tugboats push or pull on growing nerve cells, or neurons, helping them navigate to their assigned places amidst the brain's wiring.
Aug 8, 2014
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New therapeutic molecules developed at Toronto's Centre for Addiction and Mental Health (CAMH) show promise in reversing the memory loss linked to depression and aging.
Feb 14, 2019
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A well-known class of molecules, many of which are already in use therapeutically, may be able to block the Ebola virus's entry into cells and halt the disease in its tracks, according to researchers at the University of ...
Aug 7, 2015
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(Medical Xpress)—The Lassa virus is a dangerous microbe. Endemic to West Africa and spread by a rodent, it causes infections in humans that can lead to a severe and deadly hemorrhagic fever. There are an estimated 500,000 ...
Jun 27, 2014
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An international team of scientists and pharmaceutical collaborators has made a breakthrough "bench to bedside" discovery, ten years in the making, which they hope will advance the future treatment of Alzheimer's disease ...
Nov 26, 2021
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