Neuroscience

Key protein identified for brain stem cell longevity

A receptor that was first identified as necessary for insulin action, that also is located on the neural stem cells found deep in the brains of mice, is pivotal for brain stem cell longevity, according to a Rutgers study, ...

Medical research

Scientists illuminate mechanism of common drug target

Roughly a third of all drugs approved by the U.S. Food and Drug Administration target a large family of biomolecules, known as G protein-coupled receptors (GPCRs), whose job is to trigger cellular responses to extracellular ...

Oncology & Cancer

Solving the mystery of a stubborn, and common, cancer gene

One of the major successes of decades of cancer research has been the development of drugs that specifically inactivate oncogenes, genes that function abnormally, causing cells to behave erratically, become malignant and ...

Medical research

Nanobody-drug conjugates hijack the human vitamin B12 uptake route

A major challenge in cancer therapy is selectively targeting cancer cells over healthy ones. A recent study by the Locher group (IMBB) describes the development of camelid single-domain antibodies (nanobodies) that selectively ...

Diseases, Conditions, Syndromes

Omicron's secrets revealed under a microscope

Several weeks ago, Lausanne became home to some of the world's most powerful electron microscopes. They're installed at the Dubochet Center for Imaging (DCI)—a joint research facility run by Ecole Polytechnique Federale ...

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