Rapid communication of neurons in the brain, as well as the ability to learn, fundamentally rely on neurotransmitter receptors located in the contact sites of neurons, the synapses. The most important receptors in the mammalian ...
Oct 15, 2019
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Researchers from Utrecht University have clarified the function of proteins that play a role in signal transmission between neurons. Without these proteins, it is more difficult to pass on nerve stimuli, which may play a ...
Oct 9, 2019
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Biomedical engineers at Duke University have developed a method to address failures in a promising anti-cancer drug, bringing together tools from genome engineering, protein engineering and biomaterials science to improve ...
Sep 16, 2019
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Fibrosis, the damaging build-up of hardened or scarred tissue in the body, is a hallmark of various diseases and can lead to the dysfunction and failure of organs such as the heart and kidney. Fibrosis-related diseases in ...
Sep 12, 2019
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Researchers at the Paul Scherrer Institute, together with colleagues from the pharmaceutical company F. Hoffmann-La Roche AG, have taken an important step toward the development of an agent against the metastasis of certain ...
Aug 22, 2019
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A study led by scientists at the Institute for Research in Biomedicine (IRB Barcelona) and published in Nature Communications proposes chaperone protein Hps70 as an attractive therapeutic target for the treatment of Kennedy's ...
Aug 8, 2019
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Researchers have long known that dozens of inherited diseases, called toxic proteinopathies, are caused by the build-up of specific misfolded proteins in cells. But, the molecular mechanisms responsible for this accumulation ...
Jul 25, 2019
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A new study using a special type of electron microscope using samples cooled to extremely cold temperatures provides critical information for drug developers seeking to reduce nausea and vomiting side effects of cancer treatments. ...
Jul 22, 2019
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Cytokines, small proteins released by immune cells to communicate with each other, have for some time been investigated as a potential cancer treatment.
Jun 26, 2019
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Natural killer cells are part of the innate immune system. Their role is to detect virus-infected cells and destroy them. When an infection is detected, a small subset of the most effective killer cells is identified and ...
Jun 3, 2019
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