G protein-coupled receptors (GPCRs) are the largest family of membrane protein receptors. The proteins control how tissues and organs function. More than one-third of current drugs target these receptors.
Nov 5, 2020
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Where in a nerve cell is a certain receptor protein located? Without an answer to this question, it is difficult to draw firm conclusions about the function of this protein. Two scientists at the Max Planck Institute of Neurobiology ...
Nov 2, 2020
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Scientists at Scripps Research have comprehensively mapped how a key class of proteins within cells regulates signals coming in from cell surface receptors.
Oct 2, 2020
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Following reports in June that the cheap steroid drug dexamethasone could help treat patients severely ill with COVID-19, scientists and clinicians urged caution. They were careful to highlight the need for further study ...
Sep 8, 2020
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As the COVID-19 pandemic continues to spread, scientists and health care providers are seeking ways to keep the coronavirus from infecting tissues once they're exposed. A new study suggests luring the virus with a decoy—an ...
Aug 4, 2020
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UCLA researchers have launched a new clinical trial that uses a hormone suppresser commonly used to treat men with prostate cancer to help improve clinical outcomes for men infected with COVID-19.
May 15, 2020
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In the search for treatments for COVID-19, many researchers are focusing their attention on a specific protein that allows the virus to infect human cells. Called the angiotensin-converting enzyme 2, or ACE2 "receptor," the ...
May 14, 2020
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One of the defining features of Covid-19 is the excessive immune response that can occur in severe cases. This burst of immune overreaction, also called a cytokine storm, damages the lungs and can be fatal.
Apr 16, 2020
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A commonly expressed protein in skin—periostin—can directly activate itch-associated neurons in the skin, according to new research from North Carolina State University. The researchers found that blocking periostin receptors ...
Apr 7, 2020
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In hopes of developing a possible treatment for COVID-19, a team of MIT chemists has designed a drug candidate that they believe may block coronaviruses' ability to enter human cells. The potential drug is a short protein ...
Mar 30, 2020
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