A type of immune therapy called chimeric antigen receptor (CAR)-T cell therapy has revolutionized the treatment of multiple types of blood cancers but has shown limited efficacy against glioblastoma—the deadliest type of ...
Mar 13, 2023
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Unlike other forms of blood cancer, acute myeloid leukemia (AML) cannot currently be treated with CAR-T cell immunotherapy. The reason is that specific molecular targets with which certain immune cells could specifically ...
Mar 13, 2023
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51
Scientists from German Cancer Research Center (DKFZ), together with colleagues from Germany, Israel, and the U.S., have found that the gut microbiome may modulate the efficacy of CAR-T cellular immunotherapy CAR-T cells in ...
Mar 13, 2023
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Estrogen is known to play an important role in the protection of women's hearts, but once women are postmenopausal and estrogen levels drop, they are at an increased risk of a number of diseases and conditions, including ...
Mar 10, 2023
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For the first time, researchers examine the effects of gender-affirming androgen therapy on breast tissue in transgender men with single-cell resolution. Their results give an unprecedented look into the changes that occur ...
Mar 8, 2023
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A multifaceted intervention to improve prescribing practices increased the likelihood that patients with type 2 diabetes and heart disease would be prescribed three classes of guideline-recommended medications by more than ...
Mar 7, 2023
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Blood cancer patients, especially when they relapse, have a poor prognosis, and generally do not survive very long. The last five years have seen success in treating these patients with Chimeric Antigen Receptor (CAR) T-cells—a ...
Feb 24, 2023
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Post-partum depression (PPD) develops after childbirth and affects both the mother's and the infant's health by preventing healthy bonding. Women with PPD experience intense anxiety, feelings of depression, sleeplessness, ...
Feb 20, 2023
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Universitätsklinikum Erlangen is the first in the world to use CAR T-cells to successfully treat a patient suffering from a severe case of muscle inflammation (myositis). The disease is triggered by a malfunction in the ...
Feb 20, 2023
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Location, location, location is the key for psychedelic drugs that could treat mental illness by rapidly rebuilding connections between nerve cells. In a paper published in Science, researchers at the University of California, ...
Feb 16, 2023
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