Genetics

Olfactory neurons adapt to the surrounding environment

Olfactory receptors, present on the surface of sensory neurons in the nasal cavity, recognize odorant molecules and relay this information to the brain. How do these neurons manage to detect a large variability of signals ...

Neuroscience

Synaptic connectivity of a novel cell population in the striatum

A new study from the Department of Neuroscience at Karolinska Institutet characterizes a novel neuronal population in the basal ganglia, responsible for the interaction between two types of neurotransmitters, GABA and acetylcholine. ...

Neuroscience

Scientists identify how the brain links memories

Our brains rarely record single memories—instead, they store memories into groups so that the recollection of one significant memory triggers the recall of others connected by time. As we age, however, our brains gradually ...

Medical research

Protein linked to intellectual disability has complex role

Fragile X syndrome, the leading inherited cause of intellectual disability, is due to a genetic mutation that largely eliminates the fragile X protein, a critical element of normal brain development and function.

Neuroscience

Key protein identified for brain stem cell longevity

A receptor that was first identified as necessary for insulin action, that also is located on the neural stem cells found deep in the brains of mice, is pivotal for brain stem cell longevity, according to a Rutgers study, ...

Oncology & Cancer

New regulator of prostate cancer metastasis discovered

A transcription factor normally associated with androgen receptor activity in prostate cancer has a newly discovered role in controlling lipid biosynthesis, according to a Northwestern Medicine study published in Nature Genetics.

Obstetrics & gynaecology

Discovering a mysterious estrogen's important role in pregnancy

When a woman becomes pregnant, her levels of estriol, one of the three common estrogens that are nearly undetectable before conception, skyrocket. However, scientists never knew what this hormone does or why levels of it ...

Oncology & Cancer

Research team discovers new target for CAR T cells in solid tumors

Chimeric antigen receptor T-cell therapy, or CAR T, has made a big impact on the treatment of certain blood cancers, allowing patients with relapsed/refractory disease to live longer, healthier lives. But in clinical study, ...

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